Journal: Frontiers in Pharmacology
Article Title: Enhanced therapeutic potential of paeoniflorin and vitamin B12 in intracerebropeduncle ethidium bromide-induced multiple sclerosis-like pathology
doi: 10.3389/fphar.2026.1792674
Figure Lengend Snippet: (A–C) PNN neuroprotective role in mitigating EBRO-induced alterations in levels of apoptotic markers like Bax (A) , Bcl-2 (B) , and Caspase-3 (C) in brain homogenates. To identify significant differences between groups, a one-way ANOVA and Tukey’s post hoc test were used for statistical analysis (A–C) . The statistical significance level was set at p < 0.01, and the data were displayed as mean ± standard deviation (SD). There were eight wistar rats (n = 8) in each experimental group. β v/s Sham Control, Vehicle Control, and PNN Perse; δ v/s EBRO; δα1 v/s EBRO + PNN50; δα2 v/s EBRO + PNN100, EBRO + PNN50; and δα3 v/s EBRO + VB12 (30), EBRO + PNN100, EBRO + PNN50.
Article Snippet: We assessed apoptotic markers, including Bcl-2 [KLR1880; Krishgen Biosystem, Mumbai, India], Bax [KLR0034; Krishgen Biosystem, Mumbai, India], and Caspase-3 [KLR1648; Krishgen Biosystem, Mumbai, India] ( ).
Techniques: Standard Deviation, Control